Tuesday, August 19, 2008

A Cure For The Uncommon Flu

The H5N1 Virus

Scientists Have Succeed In Replicating Flu Pandemic
Antibodies From 90 Year Old Survivors

Ninety years ago the Spanish flu swept across the globe, killing between 50 and 100 million people in only a few months. Since then, the specter of another flu pandemic dealing death and woe around the world has periodically terrified the medical and popular communities. But scientists searching for ways to prevent a similar outbreak in the form of the H5N1 bird flu have found a cure for the deadliest flu in the most unlikely place: nonagenarian immune systems.

A new paper in the journal Nature confirms that a team of doctors has succeeded in isolating pandemic-flu killing antibodies from 90+ year old survivors of the Spanish flu outbreak. To test whether or not the antibodies still worked, the doctors injected the immune cells into mice, and then dosed the mice with preserved copies of the 1918 flu recovered from frozen victims of the Spanish flu that had been buried in Alaskan permafrost. Within those mice, the antibodies and the virus renewed a microscopic battle that had lain dormant for almost a century. The mice that received a high dose of the antibodies lived, while mice that received a low dose of antibody, or none at all, died as expected.

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